(2000) Egr-1, a master switch coordinating upregulation of divergent gene families underlying ischemic stress
It is commonly written as AlaGluAspGly or AEDG
Glutathione and GSTs, which can make up to 10% of cellular proteins depending on the cell type, are essential for the neutralization of reactive electrophilic drug metabolites produced by phase I enzymes
Sterne JAC, Savovi J, Page MJ, Elbers RG, Blencowe NS, Boutron I, Cates CJ, Cheng HY, Corbett MS, Eldridge SM, et al
Ca 2+ at high concentrations promotes the aggregation of various daptomycin monomers to induce micelle formation, which would act as vehicles to deliver daptomycin to the surface of the bacterial cell membranes
Early human reports are promising