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[1] [2] The standard titration schedulestarting at 0.25 mg weekly and gradually increasing to maintenance doses of 0.5 mg, 1 mg or 2 mgis specifically designed to minimise these effects

Kiesel L, Sourouni M

In the preceding cycle, given to the data of the two groups were independent sample, MannWhitney U test was used for comparison between the two groups

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Thisse C, Degrave A, Kryukov GV, Gladyshev VN, Obrecht-Pflumio S, Krol A, Thisse B, Lescure A