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Highlights The scientists used a compound called 5-amino-1MQ to inhibit an enzyme called NNMT that plays a role in breaking down a precursor to NMN in the NAD+ synthesis pathway

PMID 27806244

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Those with diseases that affect the gut, such as Crohns disease or celiac disease, are also at risk ( Summary Those at greatest risk of vitamin B12 deficiency are vegans and vegetarians, who get little to no B12 from the diet