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The pathways of PD-1 and its associated ligand, PD-L1, are among the most thoroughly researched in the context of immune suppression caused by cancer

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J Biol Chem (2005) 280:27508.10.1074/jbc.M410242200 41 Gonzalez-DosalRHoranKARahbekSHIchijoHChenZJMieyalJJet alHSV infection induces production of ROS, which potentiate signaling from pattern recognition receptors: role for S-glutathionylation of TRAF3 and 6