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Semaglutide GLP-1 and Ozempic are both GLP-1 receptor agonists used to manage weight and type 2 diabetes, but they differ in their primary purposes
Zelniker TA, Wiviott SD, Raz I, Im K, Goodrich EL, Furtado RHM, et al
Blood Pressure: Despite the slight rise in heart rate, most patients experience a significant drop in systolic and diastolic blood pressure
Stress Incontinence and Pelvic Floor Muscles The use of Ozempic can lead to stress incontinence, especially because the quick weight loss associated with it places pressure on the pelvic floor muscles
[2] The head-to-head ACHIEVE-3 trial, published in The Lancet in February 2026, compared orforglipron 36 mg to oral semaglutide 14 mg in 1,698 patients with type 2 diabetes over 52 weeks