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A 0.41.0% reduction in HbA1c (glycosylated hemoglobin A1c) has been observed with monotherapy of alogliptin after 26 weeks of treatment [7]
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Faseb j 2009
Folia Med (Plovdiv)
Lactate itself functions as a potent immunomodulatory metabolite: it suppresses the cytotoxic function of CD8+ T cells and natural killer (NK) cells, inhibits dendritic cell maturation, and enhances the activity of Tregs, all of which contribute to the establishment of an immunosuppressive TME (137)
Addgene) was similar to that described in our previous work
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