Who does the article say should not combine them
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Moreover, focal amplification of chromosomal elements onto eccDNA can alter their regulatory context, often releasing genes and/or transposable elements from chromosomal constraints
[8] Although not an absolute contraindication, patients with coronary artery disease or unstable angina should only use B-Complex injections containing niacinamide under physician supervision, since high-dose niacin supplements have been linked to arrhythmias in such patients
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